Chemical reporters for biological discovery
WebApr 15, 2024 · Chemical tools to study biological processes with molecular detail are foundational to modern science. The advent of recombinant protein expression enabled tracking protein dynamics in living... WebMy Research and Language Selection Sign into My Research Create My Research Account English; Help and support. Support Center Find answers to questions about …
Chemical reporters for biological discovery
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WebSci-Hub Chemical reporters for biological discovery. Nature Chemical Biology, 9 (8), 475–484 10.1038/nchembio.1296 sci hub to open science ↓ save Grammel, M., & … WebJun 14, 2024 · Here we review how chemical reporters in conjunction with bioorthogonal labeling methods can be used to image and retrieve nucleic acids, proteins, glycans, …
WebHere we review how chemical reporters in conjunction with bioorthogonal labeling methods can be used to image and retrieve nucleic acids, proteins, glycans, lipids and … WebBioorthogonal Reporters for Detecting and Profiling Protein Acetylation and Acylation Abstract Protein acylation, exemplified by lysine acetylation, is a type of indispensable and widespread protein posttranslational modification in eukaryotes.
WebSep 20, 2011 · Bioorthogonal chemical reporters for analyzing protein lipidation and lipid trafficking. Protein lipidation and lipid trafficking control many key biological functions in … WebJul 22, 2024 · The dynamic change of cell-surface glycans is involved in diverse biological and pathological events such as oncogenesis and metastasis. ... Although this chemical reporter technique has dominated glycosylation investigation thus far, selective ... M. Grammel, H. C. Hang, Chemical reporters for biological discovery. Nat. Chem. Biol. …
WebWe aim to provide the possibility for every chemical biologist to meet and discuss with peers on topics ranging from tool development to biological applications, from computational drug design to synthetic chemistry. Session topics. Drug and target discovery; Genetically-encoded biosensors; Structure-function relations in chemical …
Webadvances in bioorthogonal chemical reporters that have enabled the imaging and functional analysis of nucleic acids, proteins, glycans, lipids and other metabolites in … toyworld unicornWebFeb 14, 2014 · Joris Vriens Katharina Held Thomas Voets Article 05 Jan 2014 An optogenetic gene expression system with rapid activation and deactivation kinetics Optogenetic systems permit the temporal and... toyworld victor harborWebApr 26, 2024 · Herein, we report an alkynyl-functionalized bioorthogonal chemical reporter, YnLac, for the detection and identification of protein lactylation in mammalian cells. Our … thermopompe acd 12000 btuWebSep 20, 2011 · Bioorthogonal chemical reporters for analyzing protein lipidation and lipid trafficking Protein lipidation and lipid trafficking control many key biological functions in all kingdoms of life. thermopompe achatWebThe attachment of lipids onto proteins modulates the activity of proteins in many biological settings. The analysis of protein lipidation, however, is challenging due to the relatively few methods for the detection of lipid-modified proteins. Here we describe the synthesis of ω-azido-fatty acids as non-radioactive chemical probes for the rapid visualization of fatty … toyworld voucherWebHerein, we integrate this feature into the bioorthogonal chemical reporter strategy, which enables visible light-controlled spatiotemporal labeling of cell-surface glycans, lipids, and … toyworld usWebApr 14, 2024 · Herpesviral nuclear egress is a regulated process of viral capsid nucleocytoplasmic release. Due to the large capsid size, a regular transport via the nuclear pores is unfeasible, so that a multistage-regulated export pathway through the nuclear lamina and both leaflets of the nuclear membrane has evolved. This process involves … toyworld victoria