Phospho-drp1 ser616
WebApr 29, 2024 · Previous studies have shown that Ca 2+ /calmodulin-dependent protein kinase Iα (CaMKIα), kinase II (CaMKII), and CDK1 promote the phosphorylation of Drp1 at Ser616 and increase Drp1 ... WebMay 5, 2024 · The number of (Ser616) phospho-Drp1 clusters was quantified using NIH ImageJ software in a similar way to the method for quantifying mitochondrial fragmentation. A confocal immunofluorescence image of cells’ (Ser616) phospho-Drp1 clusters was imported to ImageJ.
Phospho-drp1 ser616
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WebNov 20, 2024 · As the phosphorylation of Drp1 at Ser616 was reported to be essential to its GTPase activity as well as mitochondrial fission [19], we further detected the level of phospho-Drp1 at Ser616 in the corneas after alkali burn by western blotting assay and immunofluorescence staining.As shown in Fig. 2 A and B, the phosphorylation level of … WebJun 2, 2024 · Significantly, reduced detection of Drp1 S616 phosphorylation is shown in fibroblasts derived from 4 PD patients harboring PINK1 mutants and 4 out of 7 sporadic …
Web1 day ago · Non-lethal caspase activation (NLCA) has been linked to neurodevelopmental processes. However, how neurons control NLCA remains elusive. Here, we focu… WebAug 30, 2024 · The ISO reduced the expression of mitofusin 2 (Mfn2) and increased the expression of dynamin-related peptide 1 (Drp1) in NRCMs, which was accompanied by an increase of Drp1-Ser616 phosphorylation ...
WebJul 13, 2024 · In the zoomed images, the yellow color indicates DRP1 or phospho-DRP1 (Ser616) in mitochondria. Scale bar 10 μM. *P < 0.05, **P < 0.01, ***P < 0.001. Full size image. Given the important role of ...
WebPhospho (Ser616) View Product On Supplier's Website Request a Quote from Cell Signaling Technology Supplier provided information Immunogen Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser616 of human DRP1.
WebThe glomerular expression of Drp1, phospho-Drp1 (Ser616) and Fis1, urinary protein measurements, and podocyte mitochondrial density under electron microscopy were investigated and compared. Results: Glomerular expression of Drp1, phospho-Drp1 (Ser616) and Fis1 was mainly increased in children with NS with membranous nephropathy. floating tv cabinet heightWebThe Phospho-DRP1 (Ser616) Antibody was generated using DNM1L, and dynamin 1 like as the antigen and it reacts with Human. Phospho-DRP1 (Ser616) Antibody detects … floating tv cabinet with hidden tvWebSep 26, 2024 · We performed an immunohistochemistry analysis of Drp1 and phospho-Drp1 Ser616 on 106 pair-matched pre-neoCRT biopsies and post-neoCRT surgical tissues in … floating turtle traps for pondsWebPhospho-DRP1 (Ser616) Antibody detects endogenous levels of DRP1 only when phosphorylated at Ser616. Species Reactivity: Human. Species … great lakes concrete and pavingWebSep 26, 2024 · A strikingly elevated phosphorylation of activated Drp1 (Ser616) was observed following the chemotherapeutic drug OXP treatment (Fig. 1b) But there is no variation on mitochondrial proteins... floating tv cabinet installationWebMay 27, 2024 · Antibodies against Phospho-RIP3 (Thr231/Ser232) and Phospho-Drp1 (Ser616) were purchased from Cell Signaling Technology (Danvers, MA, USA). The Aggresome Detection Kit was acquired from Abcam (Cambridge, MA, USA). MitoTracker Deep Red, the ROS 2′,7′-dichlorodihydrofluorescein diacetate (DCFH-DA) kit, … great lakes computer source inc grand rapidsWebPhospho-DRP1 (Ser616) (D9A1) Rabbit mAb recognizes endogenous levels of DRP1 protein only when phosphorylated at Ser616. Species Reactivity: Human, Mouse. Species … great lakes concrete coatings